{"id":14429,"date":"2024-10-16T21:36:51","date_gmt":"2024-10-16T21:36:51","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/astm-e2526-2008\/"},"modified":"2024-10-24T12:01:01","modified_gmt":"2024-10-24T12:01:01","slug":"astm-e2526-2008","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/astm\/astm-e2526-2008\/","title":{"rendered":"ASTM-E2526 2008"},"content":{"rendered":"<\/p>\n<p id=\"s00002\">1.1 This test method provides a methodology to assess the cytotoxicity of suspensions of nanoparticulate materials in porcine proximal tubule cells (LLC-PK1) and human hepatocarcinoma cells (Hep G2) which represents potential target organs following systemic administration<\/p>\n<p id=\"s00003\">1.2 This test method is part of the <span class=\"italic\">in vitro<\/span> preclinical characterization cascade.<\/p>\n<p id=\"s00004\">1.3 This test method consists of a protocol utilizing two methods for estimation of cytotoxicity, 3-(4,5-Dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) reduction and lactate dehydrogenase (LDH) release.<\/p>\n<p id=\"s00005\">1.4 <span class=\"italic\">This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.<\/span><\/p>\n<p><h4>PDF Catalog<\/h4>\n<table border=\"1px\" class=\"des-table\">\n<tr>\n<th>PDF Pages<\/th>\n<th>PDF Title<\/th>\n<\/tr>\n<tr>\n<td><b>1<b><\/td>\n<td>Scope <br \/> Referenced Documents <br \/> Terminology <br \/> Summary of Test Method <br \/> Significance and Use  <\/td>\n<\/tr>\n<tr>\n<td><b>2<b><\/td>\n<td>Reagents and Materials <br \/> Experimental Procedure  <\/td>\n<\/tr>\n<tr>\n<td><b>3<b><\/td>\n<td>FIG. 1   <\/td>\n<\/tr>\n<tr>\n<td><b>4<b><\/td>\n<td>Calculation or Interpretation of Results <br \/> FIG. 2   <\/td>\n<\/tr>\n<tr>\n<td><b>5<b><\/td>\n<td>FIG. 3   <\/td>\n<\/tr>\n<tr>\n<td><b>6<b><\/td>\n<td>Rationale <br \/> Precision and Bias <br \/> Keywords  <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p><b>E2526-08 Standard Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials in Porcine Kidney Cells and Human Hepatocarcinoma Cells<\/b><\/p>\n<table class=\"shortdes-table\" style=\"width: 100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>Published By<\/td>\n<td>Publication Date<\/td>\n<td>Number of Pages<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/pdfstandards.shop\/product-category\/publishers\/astm\/\"><b>ASTM<\/b><\/a><\/td>\n<td>2008<\/td>\n<td>6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":14430,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[122,2637],"product_tag":[],"class_list":{"0":"post-14429","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-07-100-10","7":"product_cat-astm","9":"first","10":"instock","11":"sold-individually","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/14429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/14430"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=14429"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=14429"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=14429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}